Evidence-Based Information

Clinical Resources & Expert Guidance

Evidence-based information about opioid addiction, treatment options, and recovery science. Connect with professional support for lasting change.

Research-backed information
From OpioidAddiction.ai
Expert reviewed

Understanding Treatment Options

Learn about the evidence-based approaches that help people achieve lasting recovery

Medication-Assisted Treatment (MAT)

Combines FDA-approved medications with counseling and behavioral therapies to provide a whole-patient approach to treating substance use disorders.

  • Buprenorphine (Suboxone)
  • Methadone
  • Naltrexone (Vivitrol)
Learn More

Behavioral Therapies

Evidence-based talk therapies that help modify behaviors, manage stress, and develop coping skills for long-term recovery.

  • Cognitive Behavioral Therapy (CBT)
  • Dialectical Behavior Therapy (DBT)
  • Contingency Management
Learn More

Detoxification Programs

Medically supervised programs that help safely manage withdrawal symptoms when stopping opioid use.

  • Inpatient detox
  • Outpatient detox
  • Medication-supported detox
Learn More

Inpatient Treatment

Residential programs providing 24/7 support, structure, and intensive therapy in a controlled environment.

  • Residential rehab (30-90+ days)
  • Individual & group therapy
  • Aftercare planning
Learn More

Outpatient Programs

Flexible treatment programs that allow you to live at home while attending scheduled therapy sessions.

  • PHP (Partial Hospitalization)
  • Intensive Outpatient (IOP)
  • Standard outpatient
Learn More

Support Groups

Peer-led groups providing mutual support, shared experiences, and community connection for sustained recovery.

  • 12-step programs (AA/NA)
  • SMART Recovery
  • Secular Organizations
Learn More
The Science

Understanding Opioid Addiction

Opioid use disorder is a medical condition affecting the brain. Understanding the science helps remove shame and stigma, making it easier to seek treatment.

Brain Chemistry

Opioids bind to receptors in the brain, releasing dopamine and creating feelings of pleasure that can lead to compulsive use.

It's Not a Choice

Addiction changes brain structure and function. Willpower alone cannot override these changes—this is why treatment works.

Recovery Is Possible

The brain can heal. With proper treatment and support, people recover and live fulfilling lives in long-term sobriety.

Deeper Science

Recovery Statistics

MAT Effectiveness (reduced opioid use) 70%+
People who seek treatment and improve 50%+
Reduction in overdose risk with MAT 40-60%
Improvement in quality of life 80%+

Statistics from SAMHSA, NIDA, and peer-reviewed research studies.

Finding the Right Treatment

Every recovery journey is unique. Here's how to find the support that fits your needs

1

Call a Helpline

SAMHSA's National Helpline (1-800-662-4357) provides free, confidential treatment referrals 24/7, in English and Spanish.

SAMHSA Helpline

1-800-662-4357

2

Find Local Treatment

Use SAMHSA's treatment locator to find licensed providers, MAT programs, and support services near you.

FindTreatment.gov

Find local providers

3

Consult a Professional

Talk to your doctor about MAT options. They can help create a personalized treatment plan that addresses your specific needs.

Questions to ask

"Is MAT right for me?"

Questions to Ask Your Treatment Provider

About Medications

  • • What MAT options do you offer?
  • • How long will I be on medication?
  • • What are the side effects?

About Schedule

  • • What does a typical day look like?
  • • How many hours per week?
  • • Is there flexibility for work?

About Costs

  • • Do you accept my insurance?
  • • What is self-pay cost?
  • • Are there payment plans?

About Aftercare

  • • What support after treatment?
  • • Alumni programs available?
  • • Relapse prevention planning?
Know the Signs

When to Seek Help

Recognizing the signs of opioid use disorder is the first step toward recovery. You don't have to wait for a crisis to ask for help.

Taking more than intended

Using more opioids than you planned, or for longer than intended

Spending time obtaining opioids

Significant time spent getting, using, or recovering from opioids

Cravings

Strong urges or cravings to use opioids that are hard to resist

Continuing despite problems

Using opioids despite relationship or work problems it causes

Tolerance & withdrawal

Needing more to get the same effect, or experiencing withdrawal symptoms

Get Help Now

Co-occurring Conditions

Opioid use disorder often occurs alongside other mental health conditions. Effective treatment addresses all conditions together.

Depression

Anxiety

PTSD/Trauma

Alcohol Use

Dual Diagnosis Treatment

Look for providers who offer integrated treatment for both substance use and mental health disorders.

Explore More on OpioidAddiction.ai

Access comprehensive clinical resources, treatment information, and expert guidance from our partner site dedicated to opioid addiction recovery.

24/7 Crisis Support

In Immediate Need?

If you're in crisis or having thoughts of self-harm, help is available right now.

988 Suicide & Crisis Lifeline

Call or text 988

Crisis Text Line

Text HOME to 741741

SAMHSA National Helpline

1-800-662-4357

Continue Your Recovery Journey

Use these tools alongside clinical support for a comprehensive approach to recovery

Medical Disclaimer

The information provided on this page is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, call your doctor, go to the emergency department, or call 988 immediately.